![jaws spss 22 jaws spss 22](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13023-020-01589-0/MediaObjects/13023_2020_1589_Fig1_HTML.png)
The inclusion criteria were edentulous lower jaw patients in need of rehabilitation with mandibular overdentures implant-supported. Conclusions: This study indicates that treatment of mandibular edentulous patients with overdentures by guided surgery and early loading of implants placed appears to be a successful implant protocol. Six implants (21.4%) were associated with peri-implantitis. Four patients (28.6%) showed some kind of mechanical prosthodontic complications. Mean marginal bone loss was 1.25 mm ± 0.95 mm. Fourteen overdentures were placed in the patients over the implants. Clinical outcomes showed a global success of 100% of implants. The clinical follow-up of the study was 44.7 ± 31.4 months. Nine patients (64.3%) suffered from systemic diseases (i.e., diabetes, cardiovascular diseases). Four patients (28.6%) had a previous history of periodontitis. Results and discussion: Fourteen patients (nine females and five males) were treated with 28 implants. After flapless surgery, implants were early loaded with an overdenture at 6 weeks. Patients and methods: Mandibular edentulous patients were diagnosed with an oral examination, cone-beam computerized tomography, and diagnostic casts for intermaxillary relations and treated with overdentures over two implants by guided surgery. Introduction: This study aimed to show the clinical outcomes of implants inserted by guided surgery supporting mandibular overdentures in edentulous patients.